Celiac disease - What is it?
Celiac disease is an autoimmune disease in which there is intolerance to a protein in gluten. Gluten is found in grain products, such as wheat, bread and pasta. People with a gluten allergy are hypersensitive and quickly develop complaints such as stomach pain. This is often after eating, but it can also be a while later. The best treatment for celiac disease is to avoid gluten. In the supermarket you increasingly see gluten-free alternatives.Celiac disease is an autoimmune disease in which the body's immune cells attack the intestinal mucosa. This causes atrophy of the intestinal mucosa. When a visual examination is performed, one sees smooth mucous membrane of the intestines, we call this villous atrophy. Visual examination is the best diagnostic tool, but this is a rather unpleasant method to arrive at the diagnosis. Another option is blood tests.
When there is villous atrophy, nutrients such as vitamins are not absorbed properly. This can cause fatigue, depression, anemia and osteoporosis, in addition to diarrhea and constipation. These are very diverse complaints, so celiac disease is not immediately considered.
We measure markers that demonstrate celiac disease with a blood test. This was previously done with three markers, namely endomysium IgA, anti-tTG and total IgA. The blood test for celiac disease today is accurate with just the anti-tTG.
What do we determine?
Tissue transglutaminase
Antibodies against tissue transglutaminase are based on the presence of IgA antibodies, a protein of the immune system. If there is an IgA deficiency, this test is less reliable. If this is the case and the results are in the gray zone, additional free deamidated gliadin IgG will be requested.Endomysium Antibodies
Endomysial antibodies of class IgA are not unique to the diagnosis of celiac disease, but can also occur in other diseases. The level of the titer often corresponds to the severity of the villous atrophy in celiac disease. After starting a gluten-free diet, the titer will drop within 6-12 months. Because these antibodies are not specific for the diagnosis of celiac disease, they are no longer determined nowadays.Total IgA
IgA stands for antibody A. Our immune system has many different immune cells. However, we know some of the antibodies (such as IgM, IgG and IgE). With celiac disease there is often a decrease in the concentration of IgA antibodies. If the tissue transglutaminase gives rise to this, the total IgA is also measured.Fasting test?
You do not need to be fasting for this blood test. It is important not to stop eating gluten in the weeks and days prior to this test. The results take an average of 5 working days.
€138,00
How does it work?
Professional testing
Self-tests do not always provide reliable and consistent results. That's why Labplusarts chooses to have the tests professionally administered at a testing location. We have made this process as simple as possible for you.
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Find the test that suits you
Information on various health topics and a clear overview of our extensive test offerings. Through the website, you can easily determine which test may be relevant for you. Do you need assistance in making a choice or would you like to customize your own package? Feel free to contact us.
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Choose a testing location
We conduct tests at 350+ locations across the Netherlands, ensuring there is always a location near you. During the ordering process, you can easily select your preferred testing location, and after payment, you can schedule an appointment. Choose where and when it suits you.
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Get tested
During your appointment, one of our medical professionals will collect your sample. Subsequently, your sample will be examined in the laboratory.
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Truly reliable results with understandable explanations
Because your sample is taken professionally, the results are consistent. Your test results are evaluated by one of our own doctors and accompanied by thorough advice. We believe it's important that you understand what the results mean for you. We ensure this by providing explanations about the test and the significance of your values.
There is always a location near you
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138,00
When to choose this blood test?
Choose the celiac blood test when:- You suspect have a gluten allergy
- You have misunderstood abdominal pain complaints and do not think about IBS
- You suffer from diarrhea or constipation that gets worse with eating of gluten